U Bin Kim

About

Ubin is an organic chemist from New Zealand, currently working in South Korea. With experience in both academic and industrial settings, Ubin has led process and medicinal chemistry teams supporting complex API development and drug discovery campaigns. Currently, Ubin oversees CMO/CDMO projects at MFC.

News

2025.03.25New

Ubin and his family welcomed a baby boy! 🎉 See pictures →

2024.12.02

Ubin accepted a new role at MFC as Principal Research Engineer (수석연구원), overseeing CMO/CDMO projects.

2024.06.23

New paper: "Proprietary Synthesis of the C27−C35 Fragment of Eribulin." OPRD 2024. PDF →

Publications & Patents

Patent · Process Chemistry

Method for preparing relugolix.

Kim, U. B.; Saidhareddy, P.; Yu, H.; et al.

WO2025127790A1. Filed December 10, 2024.

[Google Patents] [PDF]

Journal Article · Process Chemistry

Proprietary Synthesis of the C27–C35 Fragment of Eribulin and its Elaboration Towards the C14–C35 Sub-unit.

Kim, U B.; Samala, S.; Jung, J.; Song, J.; Lee, K-Y.; Oh, C-Y.; Shin, H.

Org. Process Res. Dev., 2024, 28, 2832–2843.

[DOI] [PDF]

Journal Article · Process Chemistry

Scalable synthesis of the C14–C23 fragment of Eribulin and Halichondrin B.

Kim, U B.¹; Samala, S.¹; et al. (¹ Equal contribution)

Bull. Korean. Chem. Soc., 2022, 43, 1367.

[DOI] [PDF]

Journal Article · Process Chemistry

Synthesis of the C1–C13 Fragment of Eribulin on a Kilogram Scale.

Kim, S. T.; Park, Y.; Kim, N.; …; Kim, U B.; Lee, K-Y.; Shin, H.

Org. Process. Res. Dev., 2022, 26, 123.

[DOI] [PDF]

Journal Article · Process Chemistry

Process Development of Tacalcitol.

Lee, S. J.; Moon, H. W.; Lee, K-Y.; Oh, C. Y.; Kim, U B.; Shin, H.

Org. Process. Res. Dev., 2021, 25, 982.

[DOI] [PDF]

Patent · Medicinal Chemistry

Heteroaryl derivatives and pharmaceutical composition for use in preventing cancer.

Kim, U B.; Lee, Y. H.; Kang, S-i; et al.

PCT/KR2020/003558. Filed March 13, 2020.

[WIPO] [PDF]

Review · Catalysis

Synergistic Dual Transition Metal Catalysis.

Kim, U B.; Jung, D. J.; Jeon, H. J.; Rathwell, K.; Lee, S.-g.

Chem. Rev., 2020, 120, 13382–13433.

[DOI] [PDF]

Book Chapter · Catalysis

Rhodium/Palladium Dual Catalysis.

Kim, U B.; Lee, S.-g.

Science of Synthesis, 2019, 1, 57.

[DOI]

Journal Article · Catalysis

Palladium-Catalyzed Divergent Cyclopropanation by Regioselective Solvent-Driven C(sp³)–H Bond Activation.

Chung, D. S.; Lee, J. S.; …; Kim, U B.; Baik, M.-H.*; Lee, S.-g.

Angew. Chem. Int. Ed., 2018, 57, 15460–15464.

[DOI] [PDF]

Journal Article · Catalysis

Rh(II)/Mg(OtBu)₂-Catalyzed Tandem One-Pot Synthesis of 1,4-Oxazepines and 1,4-Oxazines.

Ko, Y. O.; Jeon, H. J.; Jung, D. J.; Kim, U B.; Lee, S.-g.

Org. Lett., 2016, 18, 6432–6435.

[DOI] [PDF]

Journal Article · Methodology

Synthesis of ketones via organolithium addition to acid chloride using continuous flow chemistry.

Moon, S-Y.; Jung, S-H.; Kim, U B.; Kim, W-S.

RSC Adv., 2015, 5, 79385–79390.

[DOI] [PDF]

Journal Article · Methodology

A Synthetic Approach to N-Aryl Carbamates via Copper-Catalyzed Chan–Lam Coupling at Room Temperature.

Moon, S-Y.¹; Kim, U B.¹; Sung, D.-B.; Kim, W-S. (¹ Equal contribution)

J. Org. Chem., 2015, 80(3), 1856–1865.

[DOI] [PDF]

Journal Article · Total Synthesis

Total Synthesis of Chaetoquadrins H and I.

Kim, U B.; Dalebrook, A. F.; Furkert, D. P.; Brimble, M. A.

Synlett., 2013, 24(6), 723–726.

[DOI] [PDF]

Journal Article · Total Synthesis

Total synthesis of Chaetoquadrins A–C.

Kim, U B.; Furkert, D. P.; Brimble, M. A.

Org. Lett., 2013, 15, 658–661.

[DOI] [PDF]

Journal Article · Total Synthesis

Synthesis of (±) Wine Lactone and Its Analogues by a Diels–Alder Approach.

O'Connor, P. D.; Kim, U B.; Brimble, M. A.

Eur. J. Org. Chem., 2009, 4405–4411.

[DOI] [PDF]

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